共用题干 第二篇

High Stress May Damage Memory

According to a report issued in May 1998,elderly people who have consistently high
blood levels of cortisol (皮质醇）don"t score as well on memory tests as their peers with
lower levels of the stress hormone. What"s more,high levels of cortisol are also associated
with shrinking of the hippocampus（海马区）,a region of the brain that plays a key role in
learning and memory.
The findings suggest that even cortisol levels in the normal,"healthy"range can
actually accelerate brain aging.
The study results"now provide substantial evidence that long-term exposure to adrenal
(肾上腺的）stress hormones may promote hippocampal aging in normal elderly humans",
write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress
by the adrenal glands（腺）,which sit on top of the kidneys(肾）.
Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour
cortisol levels in 51 healthy volunteers,most of whom were in their 70s.
The researchers tested the volunteers" memory on six people in the increasing/high
category and five people in the decreasing/moderate group.The groups did not differ in
tests of immediate memory,but the increasing/high cortisol group had other memory
problems compared with those in the decreasing/moderate group.
The researchers also found that the total volume of the hippocampus in those in the
increasing/high group was 14% lower than those in the decreasing/moderate group,
although there were no differences in other brain regions.
The results suggest that“…brain aging can be accelerated by levels of adrenal
hormones that are not generally regarded as pathological（病态的）and that variation within
this normal range is related to variation in the rate of brain aging",write Porter and
Landfield."This further suggests that chronic stress may accelerate the worsening of the
hippocampus." It appears that when the hippocampus shrinks due to high levels of cortisol,other brain regions