共用题干 More about Alzheimer"s Disease
Scientists have developed skin tests that may be used in the future to identify people with Alzheimer"s disease and may ultimately allow physicians to predict who is at risk of get-ting this neurological disorder.
The only current means of diagnosing the disease in a living patient is a long and expen-sive series of tests that eliminate every other cause of dementia.
“Since Aloes Alzheimer described the disease nearly a century ago,people have been trying to find a way to accurately diagnose it in its early stages,“said Patricia Grady,acting director of the National Institute of Neurological Disorders and Stroke in Bethesda,Mary-land."This discovery,if confirmed,could prove a big step forward in our efforts to deal with and understand the disease.”
Alzheimer"s is the single greatest cause of mental deterioration in older people,affecting between 2.5 million and 4 million people in the United States alone. The devastating disorder gradually destroys memory and the ability to function,and eventually causes death. There is currently no known treatment for the disease.
Researches discovered that the skin cells of Alzheimer"s patients have defects that inter-fere with their ability to regulate the flow of potassium in and out of the cells.The fact that the cell defects are present in the skin suggests that Alzheimer"s results from physiological changes throughout the body,and that dementia may be the first noticeable effect of these changes as the defects affect the cells in the brain,scientists said.
The flow of potassium is especially critical in cells responsible for memory formation. The scientists also found two other defects that affect the cells"supply of calcium,another critical element.
One test developed by researches calls for growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that govemn the flow of potassium are open. Open potassium channels create a unique electrical signature.
A spokesman for the Alzheimer"s Association said that if the validity of the diagnostic
test can be proven it would be an important development,but cautioned that other promising
tests for Alzheimer"s have been disappointing. Which of the following statements about the Alzheimer"s disease is NOT true?